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Dr. Nishith Vaddeboina, Medical Oncologist

TREATMENT

Hormonal Therapy

Hormonal therapy, also called endocrine therapy, uses medicines that lower a hormone or block its effect on cancer cells. It is a standard part of care for many hormone-receptor-positive breast cancers and for many prostate cancers. It is not chemotherapy, and it is not used for cancers that do not depend on hormones. Treatment can last months or years, and side effects such as hot flushes, joint aches, or bone thinning need a plan of their own.

Who may be offered it?

The pathology has to show that the cancer uses hormones. In breast cancer that usually means estrogen or progesterone receptors. In prostate cancer, lowering testosterone is often discussed. A positive receptor does not mean every hormone medicine is suitable. Age, menopause status, other illnesses, and the stage all change the choice.

What patients can expect

  • Tablets, injections, or both, depending on the cancer
  • A defined duration, which should be explained before you start
  • Monitoring for side effects, including bone health when relevant
  • A conversation about what happens if the cancer stops responding

Questions about this topic

Is hormonal therapy the same as hormone replacement?

No. Hormone replacement adds hormones. Cancer hormonal therapy blocks or lowers them. Do not start or stop either without advice from the clinician who knows your diagnosis.

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